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Afamelanotide, an agonistic analog of α-melanocyte-stimulating hormone, in dermal phototoxicity of erythropoietic protoporphyria.

Authors
  • Minder, Elisabeth I
Type
Published Article
Journal
Expert Opinion on Investigational Drugs
Publisher
Informa UK (Taylor & Francis)
Publication Date
Dec 01, 2010
Volume
19
Issue
12
Pages
1591–1602
Identifiers
DOI: 10.1517/13543784.2010.535515
PMID: 21073357
Source
Medline
License
Unknown

Abstract

Although early, results of the first trials of afamelanotide for PP are promising and the risk-safety profile appears favorable today. We expect afamelanotide and analogs thereof to be a prospective therapeutic tool in light-related skin diseases, and in future this drug class might prove effectiveness in other medical conditions.

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