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HTLV-1 polymyositis

Authors
Journal
Neuromuscular Disorders
0960-8966
Publisher
Elsevier
Publication Date
Volume
6
Issue
3
Identifiers
DOI: 10.1016/0960-8966(96)00008-9
Keywords
  • Htlv-1
  • Polymyositis
  • Myelopathy
  • Taxgene
Disciplines
  • Chemistry

Abstract

Abstract The case is described of an HTLV-1 seropositive Jamaican woman who presented with signs and symptoms of polymyositis and myelopathy. A muscle biopsy showed features of myositis with a mononuclear inflammatory infiltrate, variation in fibre size and evidence of regeneration. Immunocytochemistry showed the mononuclear cells were composed of macrophages and T-lymphocytes suggesting a cell-mediated response. Multiplex PCR demonstrated the presence of the HTLV-1 tax gene within the muscle.

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