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Adverse drug reactions and debrisoquine/sparteine (P450IID6) polymorphism in patients with fibromyalgia.

Authors
  • Skeith, K J
  • Hussain, M S
  • Coutts, R T
  • Ramos-Remus, C
  • Avina-Zubieta, J A
  • Russell, A S
Type
Published Article
Journal
Clinical rheumatology
Publication Date
May 01, 1997
Volume
16
Issue
3
Pages
291–295
Identifiers
PMID: 9184268
Source
Medline
License
Unknown

Abstract

The problem of adverse drug reactions in fibromyalgia patients does not appear to correlate with the PM phenotype of the P450IID6 oxidative enzyme. It also is unlikely that altered xenobiotic detoxification attributable to this PM phenotype would have a significant role in the development of fibromyalgia.

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