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Advancing the field of drug delivery: taking aim at cancer.

Authors
  • Moses, Marsha A1
  • Brem, Henry
  • Langer, Robert
  • 1 The Vascular Biology Program, Children's Hospital and the Department of Surgery, Children's Hospital and Harvard Medical School, Boston, MA 02115, USA.
Type
Published Article
Journal
Cancer Cell
Publisher
Elsevier
Publication Date
November 2003
Volume
4
Issue
5
Pages
337–341
Identifiers
PMID: 14667500
Source
Medline
License
Unknown

Abstract

Drug delivery systems for cancer therapeutics have now been used by millions of patients and have resulted in the creation of new therapies as well as significantly improving existing ones. Here we discuss a number of the drug delivery systems that have been approved by regulatory authorities and that are currently in clinical use, such as controlled delivery of cancer therapeutics, local chemotherapy, polymer drug conjugates, liposomal systems, and transdermal drug delivery patches. The next generation of "smart" drug delivery approaches such as controlled release microchips are discussed as are some of the future challenges and directions in this field.

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