Following the publication of the regulatory framework by the relevant ministries, the summer of 2018 was very busy for the university teams intending to offer, from September, an advanced nursing practice course. The training programme selected mainly follows on from existing initial training programmes but there are also a number of aspects which are particularly innovative in the nursing pathway. Setting up this training requires a change in social representations, still a source of challenges. These are linked to the innovative character of this type of practice in France as well as the fact that the training is university-based. Copyright © 2019. Published by Elsevier Masson SAS.