Adrenocortical insufficiency after pituitary surgery: an audit of the reliability of the conventional short synacthen test.
- Published Article
- Publication Date
Nov 01, 2005
This study confirms that the synacthen test is of limited use in the early postoperative phase, because out of 62 patients with normal 1-week postoperative synacthen responses, 23 patients developed a test that was indicative of adrenal insufficiency over 1-3 months. Our results indicate that a large proportion of patients should be considered for hydrocortisone replacement therapy up to 3 months postoperatively followed by reassessment of the HPA axis.
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The corresponding record at NLM can be accessed at https://www.ncbi.nlm.nih.gov/pubmed/16268800