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ADHD as a Risk Factor for Infection With Covid-19.

Authors
  • Merzon, Eugene1, 2
  • Manor, Iris2, 3
  • Rotem, Ann3
  • Schneider, Tzipporah4
  • Vinker, Shlomo1, 2
  • Golan Cohen, Avivit1, 2
  • Lauden, Ari1
  • Weizman, Abraham2, 3, 5
  • Green, Ilan1, 2
  • 1 Leumit HMO, Tel-Aviv, Israel. , (Israel)
  • 2 Tel Aviv University, Israel. , (Israel)
  • 3 Geha Mental Health Center, Petah Tikva, Israel. , (Israel)
  • 4 Clalit Health Services, Bnei Brak, Israel. , (Israel)
  • 5 Felsenstein Medical Research Center, Petah Tikva, Israel. , (Israel)
Type
Published Article
Journal
Journal of Attention Disorders
Publisher
SAGE Publications
Publication Date
Nov 01, 2021
Volume
25
Issue
13
Pages
1783–1790
Identifiers
DOI: 10.1177/1087054720943271
PMID: 32697120
Source
Medline
Keywords
Language
English
License
Unknown

Abstract

Background: ADHD limits the ability to comply with Covid-19 prevention recommendations. We hypothesized that ADHD constitutes a risk factor for Covid-19 infection and that pharmacotherapy may lower that risk. Methods: Study population included all subjects (N = 14,022) registered with Leumit Health Services between February 1st and April 30, 2020, who underwent at least one Covid-19 test. Data were collected from the electronic health records. Purchasing consecutively at least three ADHD-medication-prescriptions during past year was considered drug-treatment. Results: A total of 1,416 (10.1%) subjects (aged 2 months-103 years) were Covid-19-positive.They were significantly younger, and had higher rates of ADHD (adjOR 1.58 (95% CI 1.27-1.96, p < .001) than Covid-19-negative subjects. The risk for Covid-19-Positive was higher in untreated-ADHD subjects compared to non-ADHD subjects [crudeOR 1.61 (95% CI 1.36-1.89, p < .001)], while no higher risk was detected in treated ones [crudeOR 1.07 (95% CI 0.78-1.48, p = .65)]. Conclusion: Untreated ADHD seems to constitute a risk factor for Covid-19 infection while drug-treatment ameliorates this effect.

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