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[Adenovirus-mediated transfer of anti-MDR1 ribozyme in the treatment of multidrug-resistant human lymphoma in SCID mice].

Authors
  • Xu, Dongping
  • Wang, Fusheng
  • Ohnuma, Takao
  • Jin, Lei
Type
Published Article
Journal
Zhonghua zhong liu za zhi [Chinese journal of oncology]
Publication Date
Nov 01, 2002
Volume
24
Issue
6
Pages
529–532
Identifiers
PMID: 12667317
Source
Medline
License
Unknown

Abstract

Ad-mediated transfer of 196MDR1-Rz can revert drug resistance of MDR tumor cells both in vitro and in vivo. Ad-196MDR1-Rz may be helpful as an adjuvant in the chemotherapy of P-gp mediated MDR human tumor.

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