Affordable Access

Publisher Website

Phenylselenenyl chloride in acetonitrile-water:A highly convenient reagent for hydroxyselenation of olefins and preparation of cyclic ethers from dienes

Authors
Journal
Tetrahedron
0040-4020
Publisher
Elsevier
Publication Date
Volume
41
Issue
22
Identifiers
DOI: 10.1016/s0040-4020(01)96781-x

Abstract

Abstract The reaction of phenylselenenyl chloride with olefins in aqueous acetonitrile affords β-hydroxyalkyl phenyl selenides in excellent yields, providing the most convenient method for hydroxyselenation of olefins so far reported. When the reaction was applied to conjugated dienes, monohydroxyselenated products were obtained in good to excellent yields. From non-conjugated dienes, on the other hand, cyclic ethers containing two phenylseleno groups were produced in good to excellent yields, the first step of this reaction being the hydroxyselenation of one double bond.

There are no comments yet on this publication. Be the first to share your thoughts.