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Addressing viral resistance through vaccines.

Authors
  • Laughlin, Catherine1
  • Schleif, Amanda1
  • Heilman, Carole A1
  • 1 Division of Microbiology & Infectious Diseases, National Institute of Allergy & Infectious Diseases (NIAID), NIH, 5601 Fishers Lane, Bethesda, MD 20852, USA.
Type
Published Article
Journal
Future virology
Publication Date
Jan 01, 2015
Volume
10
Issue
8
Pages
1011–1022
Identifiers
PMID: 26604979
Source
Medline
Keywords
Language
English
License
Unknown

Abstract

Antimicrobial resistance is a serious healthcare concern affecting millions of people around the world. Antiviral resistance has been viewed as a lesser threat than antibiotic resistance, but it is important to consider approaches to address this growing issue. While vaccination is a logical strategy, and has been shown to be successful many times over, next generation viral vaccines with a specific goal of curbing antiviral resistance will need to clear several hurdles including vaccine design, evaluation and implementation. This article suggests that a new model of vaccination may need to be considered: rather than focusing on public health, this model would primarily target sectors of the population who are at high risk for complications from certain infections.

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