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Effect of the thyroid on butyrate oxidation in the rat heart

Authors
Journal
Biochemical Pharmacology
0006-2952
Publisher
Elsevier
Publication Date
Volume
3
Issue
2
Identifiers
DOI: 10.1016/0006-2952(60)90024-1

Abstract

Abstract Oxidation of butyrate by rat heart homogenates in the presence of malate, nicotinamide or endogenous “sparkers” has been studied. It was found that heart homogenates from hyperthyroid rats oxidized butyrate at a higher rate than those from normal or hypothyroid animals. It is suggested that these findings may have some bearings on the mechanisms of cardiac abnormalities associated with thyroid dysfunction.

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