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Acute toxicity of micronized 8-methoxypsoralen in rodents.

Authors
  • Apostolou, A
  • Williams, R E
  • Comereski, C R
Type
Published Article
Journal
Drug and chemical toxicology
Publication Date
Jan 01, 1979
Volume
2
Issue
3
Pages
309–313
Identifiers
PMID: 546628
Source
Medline
License
Unknown

Abstract

The acute oral and intraperitoneal LD50 values of micronized 8-Methoxypsoralen were determined in rats and mice. The values obtained in the present study were lower than those previously reported. The suggestion is made that the discrepancy in the LD50 values may possibly be attributed to differences in compound particle size in the preparations used.

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