Affordable Access

Acute responses of bone specific and related markers to maximal eccentric exercise of the knee extensors and flexors in young men.

Authors
  • Huang, Tsang-Hai1
  • Lin, Jung-Charng2
  • Ma, Mi-Chia3
  • Yu, Tsung4
  • Chen, Trevor C5
  • 1 Institute of Physical Education, Health and Leisure Studies, National Cheng Kung University, Tainan City, Taiwan. , (Taiwan)
  • 2 Department of Physical Education, Chinese Culture University, Taipei City, Taiwan. , (Taiwan)
  • 3 Department of Statistics, National Cheng Kung University, Tainan City, Taiwan. , (Taiwan)
  • 4 Department of Public Health College of Medicine, National Cheng Kung University, Tainan City, Taiwan. , (Taiwan)
  • 5 Department of Physical Education, National Taiwan Normal University, Taipei City, Taiwan. , (Taiwan)
Type
Published Article
Journal
Journal of musculoskeletal & neuronal interactions
Publication Date
Jun 01, 2020
Volume
20
Issue
2
Pages
206–215
Identifiers
PMID: 32481236
Source
Medline
Keywords
Language
English
License
Unknown

Abstract

The present study determined time-course changes in plasma bone-specific and -related markers following a bout of maximal eccentric contractions (MaxEC) of bilateral knee extensors (KE) and flexors (KF). Sedentary young men (n=30) performed a bout of 10 sets of 10 MaxEC (30°/s) of KE and KF with each leg, respectively. Maximal voluntary isometric contraction (MVC) torque, muscle soreness (SOR), plasma creatine kinase (CK) activity, insulin, leptin, tumor necrosis factor-α (TNF-α), undercarboxylated-osteocalcin (ucOCN), carboxy-terminal crosslinking telopeptide of type I collagen (CTX-1) and procollagen type I N-terminal propeptide (P1NP) concentrations were measured from before to 7 days after MaxEC. Significant changes in MVC (KE: -28%, KF: -38%), SOR and plasma CK activity (peak: 39,163 IU/L) following MaxEC were evident (P<0.05) compared to baseline. Plasma leptin (17%) concentrations decreased at 1 day after MaxEC. In bone related markers, plasma ucOCN concentrations (20%) increased at 7 days after MaxEC, and plasma CTX-1 concentrations decreased at 2, 4 and 7 days after MaxEC (6~7%; P<0.05). These results demonstrate that a lean effect of bone generation and an enhanced energy anabolism can be induced by a single bout of MaxEC.

Report this publication

Statistics

Seen <100 times