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Acute phase proteins in drain fluid: a new screening tool for colorectal anastomotic leakage? APPEAL-study: Analysis of Parameters Predictive for Evident Anastomotic Leakage

Authors
  • Komen, Niels
  • Slieker, Juliette
  • Willemsen, Paul
  • Mannaerts, Guido
  • Pattyn, Piet
  • Karsten, Tom
  • de Wilt, Hans
  • van der Harst, Erwin
  • van Leeuwen, Willem
  • Murawska, Magdalena
  • Jeekel, Johannes
  • Lange, Johan F.1, 2, 1, 3, 1, 4, 1, 5, 1, 6, 1, 7, 1, 8, 9, 10, 11
  • 1 Department of Surgery
  • 2 Erasmus University Medical Center
  • 3 ZNA Middelheim
  • 4 St. Franciscus Gasthuis
  • 5 University Hospital Ghent
  • 6 Reinier de Graaf Groep
  • 7 Radboud University Nijmegen Medical Center
  • 8 Maasstad Ziekenhuis
  • 9 Department of Medical Microbiology and Infectious Diseases
  • 10 Erasmus Medical Center
  • 11 Department of Biostatistics
Type
Published Article
Journal
The American Journal of Surgery
Publisher
Elsevier
Publication Date
Jan 01, 2014
Accepted Date
Sep 16, 2013
Identifiers
DOI: 10.1016/j.amjsurg.2013.09.024
Source
Elsevier
Keywords
License
Unknown

Abstract

Lipopolysaccharide Binding Protein mediates the inflammatory response to gram negative infection. This study shows that quantitative determination in drain fluid may serve as a screening tool for colorectal anastomotic leakage.

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