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Acute lymphoblastic leukemia hand-mirror cells with OKT 8 phenotype.

Authors
  • Liso, V
  • Specchia, G
  • Pavone, V
  • Riezzo, A
  • Santorsola, D
  • De Tullio, L
  • Magno, M
Type
Published Article
Journal
Blut
Publication Date
Oct 01, 1986
Volume
53
Issue
4
Pages
315–319
Identifiers
PMID: 3463369
Source
Medline
License
Unknown

Abstract

Acute lymphoblastic leukemia with hand-mirror cells (ALL-HMC) was diagnosed in a 20-year old patient. Cytochemical investigations revealed a positive reaction for PAS and acid phosphatase. Lymphoid blast cells were studied with various monoclonal antibodies in order to determine their derivation and differentiation. The data obtained (positivity for Leu 9, OKT 11 and OKT 8) suggest that blast cells were of T lineage with OKT 8 phenotype. This report supports the phenotypic heterogeneity of ALL-HMC.

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