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[Acute leukemia in Fanconi's anemia. Report of a patient and review of the literature].

Authors
Type
Published Article
Journal
Tijdschrift voor kindergeneeskunde
Publication Date
Volume
55
Issue
2
Pages
68–72
Identifiers
PMID: 3590139
Source
Medline

Abstract

A case is reported of a 7 years old boy with Fanconi's Anemia (FA). The aplastic anemia has been treated with androgens. Six years after the confirmation of the diagnosis FA a (pre-)leukemia occurred. Because of the known complications of cytostatics in FA and the bad prognosis, the leukemia has not been treated. The boy died 4 months later. An overview of the literature shows 31 patients with acute non-lymphocytic leukemia in FA, of which the clinical course, chromosomal investigations and therapy are discussed.

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