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Acute Kidney Injury in the Setting of Knee Arthroplasty: A Case Report and Discussion Investigating Angiotensin-Converting Enzyme Inhibitors as the Culprit

Authors
  • Rosenbaum, Andrew J.1
  • Luciano, Jason A.2
  • Marburger, Robert3
  • Hume, Eric3
  • 1 Albany Medical Center, 43 New Scotland Ave, Albany, NY, 12208, USA , Albany (United States)
  • 2 University of Pittsburgh Medical Center, Division of Trauma and General Surgery, Pittsburgh, PA, USA , Pittsburgh (United States)
  • 3 Cooper University Hospital, Department of Orthopaedic Surgery, Camden, NJ, USA , Camden (United States)
Type
Published Article
Journal
HSS Journal ®
Publisher
Springer New York
Publication Date
Jan 20, 2011
Volume
7
Issue
2
Pages
183–186
Identifiers
DOI: 10.1007/s11420-010-9189-5
Source
Springer Nature
Keywords
License
Yellow

Abstract

Total knee arthroplasty (TKA) has become the predominant treatment modality for severe degenerative joint disease. With recent advancements in surgical and anesthetic technique, patients with severe comorbidities are able to have this procedure; they would have been precluded from TKA only a matter of years ago. Although many studies have investigated risk factors and the causes of perioperative morbidity and mortality in the arthroplasty patient, few have linked risk factors with specific outcomes. We present a case report that illustrates the link between the use of angiotensin-converting enzyme inhibitors and the development of postoperative acute kidney injury. While this relationship has been extensively studied in cardiac and gastric bypass patient populations, it has never been examined in the setting of joint replacement.

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