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Acute immune (idiopathic) thrombocytopenic purpura in childhood.

Authors
  • Tarantino, M D1
  • 1 Comprehensive Bleeding Disorder Center and the University of Illinois College of Medicine, Peoria, IL 61614, USA.
Type
Published Article
Journal
Blood Reviews
Publisher
Elsevier
Publication Date
March 2002
Volume
16
Issue
1
Pages
19–21
Identifiers
PMID: 11913988
Source
Medline
License
Unknown

Abstract

Acute immune (idiopathic) thrombocytopenic purpura (ITP) in childhood is most commonly a self-limiting condition with unexplained onset and resolution. In cases of severe thrombocytopenia, or situations where the condition persists beyond 6 months, treatment may be required to minimize the danger of life-threatening intracranial hemorrhage. Nonsurgical treatment options include corticosteroids, intravenous gammaglobulin (i.v.Ig), or anti-D. Specific indications, benefits, and limitations of these modalities are discussed, with recommendations for future directions in therapy.

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