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Acute felon as a complication of systemic paclitaxel therapy: case report and review of the literature.

Authors
  • Hijjawi, John B
  • Dennison, David G
Type
Published Article
Journal
Hand (New York, N.Y.)
Publication Date
Sep 01, 2007
Volume
2
Issue
3
Pages
101–103
Identifiers
DOI: 10.1007/s11552-007-9029-3
PMID: 18780067
Source
Medline
License
Unknown

Abstract

Breast cancer now affects 1 in 8 American women and the taxane agent paclitaxel (Taxol Bristol-Myers Squibb) is a major tool in the treatment of many such patients. Hand surgeons are therefore likely to encounter upper extremity complications related to the use of taxane therapy. We present an unusual case of a felon developing in a breast cancer patient on paclitaxel therapy with no antecedent history of trauma. Whereas onycholysis and subungual hemorrhage are reported complications of taxane therapy (Fig. 1), an acute felon with or without associated paronychia is an unusual and more aggressive manifestation of this drug-related nail dystrophy.

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