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The activity of satellite cells and myonuclei following 8 weeks of strength training in young men with suppressed testosterone levels.

Authors
  • Kvorning, T
  • Kadi, F
  • Schjerling, P
  • Andersen, M
  • Brixen, K
  • Suetta, C
  • Madsen, K
Type
Published Article
Journal
Acta physiologica (Oxford, England)
Publication Date
Mar 01, 2015
Volume
213
Issue
3
Pages
676–687
Identifiers
DOI: 10.1111/apha.12404
PMID: 25294097
Source
Medline
Keywords
License
Unknown

Abstract

Eight weeks of strength training enhances the myonuclear number in type II fibres, and this is largely blocked by the suppression of testosterone. The data indicate that low testosterone levels could reduce the differentiation of satellite cells to myonuclei via the bone morphogenetic proteins signalling pathway, resulting in reduced increases in lean leg mass.

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