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Active Metabolites from Dunalia spinosa Resinous Exudates

Authors
  • Erazo, Silvia
  • Rocco, Giovanna
  • Zaldivar, Mercedes
  • Delporte, Carla
  • Backhouse, Nadine
  • Castro, Consuelo
  • Belmonte, Eliana
  • Monache, Franco delle
  • Garcıía, Ruben
Type
Published Article
Journal
Zeitschrift für Naturforschung C
Publisher
Walter de Gruyter GmbH
Publication Date
Aug 01, 2008
Volume
63
Issue
7-8
Pages
492–496
Identifiers
DOI: 10.1515/znc-2008-7-804
Source
De Gruyter
Keywords
License
Green

Abstract

Dunalia spinosa, a plant used in folk medicine for toothaches, breathing problems and cleansing wounds, was found active as antimicrobial and antioxidant. A new (E)-aurone rutinoside (dunaurone) has been isolated from the aerial parts of the plant, and its structure was determined by spectroscopic means. Lupeol, ß-sitosterol, scopoletin, quercetin and withaferin A were also found. All the extracts exhibited strong antimicrobial activity while dunaurone showed only weak antimicrobial inhibition against Klebsiella pneumoniae; in addition it presented a significant free radical scavenging activity.

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