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Active Giant Cell Vasculitis Diagnosis with 68Ga PSMA PET/CT Imaging

Authors
  • Sağer, Muhammet Sait1
  • Bilgiç, Seçkin1
  • Uslu, Lebriz1
  • Asa, Sertaç1
  • Sağer, Güneş2
  • Sönmezoğlu, Kerim1
  • 1 İstanbul University-Cerrahpaşa, Cerrahpaşa Faculty of Medicine, Department of Nuclear Medicine, İstanbul, Turkey
  • 2 Kartal Dr. Lütfi Kırdar City Hospital, Clinic of Pediatry, İstanbul, Turkey
Type
Published Article
Journal
Molecular Imaging and Radionuclide Therapy
Publisher
Galenos Publishing
Publication Date
Feb 09, 2021
Volume
30
Issue
1
Pages
57–59
Identifiers
DOI: 10.4274/mirt.galenos.2019.90532
PMID: 33586411
PMCID: PMC7885283
Source
PubMed Central
Keywords
Disciplines
  • Interesting Image
License
Green

Abstract

Vasculitis is a multisystem disease characterized by inflammation with infiltration of leukocytes into the blood vessels. Giant cell arteritis (GCA) is the most common form of vasculitis that mostly affects medium- and large-sized arteries. 18Fluorine-fluorodeoxyglucose (18F-FDG) positron emission tomography/computed tomography (PET/CT) is increasingly used to diagnose inflammation of large arteries in GCA. Galium-68 prostate-specific membrane antigen (PSMA) PET/CT has a vital role in the assessment of patients with prostate cancer for recurrence and metastasis of the disease. Various benign and non-prostate malignant conditions may give rise to increased PSMA uptake. Herein, we demonstrate that PSMA uptake can be seen in GCA.

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