Affordable Access

deepdyve-link deepdyve-link
Publisher Website

Activation of NF-kappaB is a novel target of KRAS-induced endometrial carcinogenesis.

Authors
  • Mizumoto, Yasunari
  • Kyo, Satoru
  • Kiyono, Tohru
  • Takakura, Masahiro
  • Nakamura, Mitsuhiro
  • Maida, Yoshiko
  • Mori, Noriko
  • Bono, Yukiko
  • Sakurai, Hiroaki
  • Inoue, Masaki
Type
Published Article
Journal
Clinical cancer research : an official journal of the American Association for Cancer Research
Publication Date
Mar 15, 2011
Volume
17
Issue
6
Pages
1341–1350
Identifiers
DOI: 10.1158/1078-0432.CCR-10-2291
PMID: 21411444
Source
Medline
License
Unknown

Abstract

These findings clearly show that NF-κB activation is a novel target of oncogenic KRAS in endometrial carcinogenesis, implying the potential utility of NF-κB inhibitors for endometrial cancer chemoprevention, especially with KRAS mutation.

Report this publication

Statistics

Seen <100 times