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Activation of MMP-2 and MMP-9 in patients with oral squamous cell carcinoma.

Authors
Type
Published Article
Journal
Journal of Surgical Oncology
0022-4790
Publisher
Wiley Blackwell (John Wiley & Sons)
Publication Date
Volume
90
Issue
2
Pages
81–88
Identifiers
PMID: 15844188
Source
Medline

Abstract

The study concluded that activation of MMP-2 and MMP-9 was significantly higher in malignant tissues as compared to adjacent normal tissues. Further, activation ratio of MMP-2 was significantly elevated in patients with lymph node metastasis as compared to patients without lymph node metastasis, which could predict risk of lymph node metastasis development in node negative patients.

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