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Activated Rho kinase mediates diabetes-induced elevation of vascular arginase activation and contributes to impaired corpora cavernosa relaxation: possible involvement of p38 MAPK activation.

Authors
  • Toque, Haroldo A1
  • Nunes, Kenia P
  • Yao, Lin
  • Liao, James K
  • Webb, R Clinton
  • Caldwell, Ruth B
  • Caldwell, R William
  • 1 Department of Pharmacology & Toxicology, Georgia Health Sciences University, Augusta, GA 30912-2300, USA. [email protected] , (Georgia)
Type
Published Article
Journal
Journal of Sexual Medicine
Publisher
Elsevier
Publication Date
Jun 01, 2013
Volume
10
Issue
6
Pages
1502–1515
Identifiers
DOI: 10.1111/jsm.12134
PMID: 23566117
Source
Medline
License
Unknown

Abstract

ROCK 2, p38 MAPK and arginase play key roles in diabetes-induced impairment of CC relaxation.

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