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[ACE-inhibitor induced angioedema].

Authors
Type
Published Article
Journal
Laryngo- rhino- otologie
Publication Date
Volume
86
Issue
11
Identifiers
PMID: 17966084
Source
Medline

Abstract

ACE-inhibitor induced angioedema is a non-allergic drug-related side effect. Inhibited bradykinin degradation leads to an unphysiological enhanced bradykinin plasma level with vascular leakage and, consequently, to angioedema. ACE-inhibitor induced angioedema develop rapidly in the head and neck region. Typical sites of manifestation are lips, tongue, and larynx. Novel pharmacotherapies may allow a causal treatment of the ACE-inhibitor induced angioedema in the future.

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