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Accidental five fold overdose of propofol for induction in a 38-days-old infant undergoing emergency bilateral inguinal hernia repair.

Authors
Type
Published Article
Journal
Saudi journal of anaesthesia
Publication Date
Volume
5
Issue
4
Pages
417–418
Identifiers
DOI: 10.4103/1658-354X.87273
PMID: 22144931
Source
Medline
Keywords
License
Unknown

Abstract

The induction dose of propofol is higher in younger children (2.9 mg/kg for infants younger than 2 years) than in older children (2.2 mg/kg for children 6-12 years of age). A modest reduction in systolic blood pressure often accompanies bolus administration. The major concern with propofol is the potential for propofol infusion syndrome (lactic acidosis, rhabdomyolysis, cardiac and renal failure), which is generally associated with high-dose infusion for an extended period. We report a 38-days-old male infant underwent emergency bilateral inguinal hernia repair who accidentally received a five-fold dose of propofol for induction of general anesthesia.

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