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Acceptability and compliance with daily injections of procaine penicillin in the outpatient treatment of syphilis-treponemal infection.

Authors
  • Crowe, G
  • Theodore, C
  • Forster, G E
  • Goh, B T
Type
Published Article
Journal
Sexually Transmitted Diseases
Publisher
Ovid Technologies (Wolters Kluwer) - Lippincott Williams & Wilkins
Publication Date
Mar 01, 1997
Volume
24
Issue
3
Pages
127–130
Identifiers
PMID: 9132978
Source
Medline
License
Unknown

Abstract

Daily procaine penicillin is a well-accepted out-patient regimen with excellent compliance (88% overall) and minimal side effects. Because the high-dose regimen has been shown to achieve treponemicidal levels of penicillin in the cerebrospinal fluid, it is recommended for patients with neurosyphilis or those in whom neurosyphilis cannot be excluded. It also could be considered for patients with concomitant human immunodeficiency virus infection in view of the possible progression to neurosyphilis in those treated with depot penicillin.

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