Affordable Access

Publisher Website

Epidermal mucinosis in mycosis fungoides

Authors
Journal
Journal of the American Academy of Dermatology
0190-9622
Publisher
Elsevier
Publication Date
Volume
15
Issue
1
Identifiers
DOI: 10.1016/s0190-9622(86)70147-3
Disciplines
  • Biology
  • Medicine

Abstract

In many cases of mycosis fungoides there is widening of the epidermal intercellular spaces (i.e., spongiosis) and papillary dermal fibrosis with minimal papillary dermal edema. Twenty biopsies of mycosis fungoides, stained with a modified colloidal iron procedure, were analyzed to substantiate the notion that the spongiosis resulted from the formation of an osmotic gradient because of intercellular acidic mucopolysaccharide deposition. In nineteen of twenty cases of patch-plaque mycosis fungoides, there was positive intercellular deposition of acidic mucopolysaccharides. In addition to the contribution of acidic mucopolysaccharides to the process of spongiosis, the biologic significance of epidermal mucin deposition is discussed. Mycosis fungoides should be added to the growing list of diseases in which there is epidermal mucinosis. (J Am Acad Dermatol 15:83-86, 1986.)

There are no comments yet on this publication. Be the first to share your thoughts.

Statistics

Seen <100 times
0 Comments

More articles like this

Epidermal mucinosis in mycosis fungoides.

on Journal of the American Academ... July 1986

Mucinosis of the mammary areolae and mycosis fungo...

on Clinical and experimental derm... September 1996

[MUCINOSIS FOLLICULARIS AND MYCOSIS FUNGOIDES].

on Bulletin de la Société franc... 1964

Mycosis fungoides and follicular mucinosis.

on Archives of Dermatology December 2002
More articles like this..