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Mutator activity inSchizophyllum commune

Authors
Journal
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis
0027-5107
Publisher
Elsevier
Publication Date
Volume
107
Issue
1
Identifiers
DOI: 10.1016/0027-5107(83)90077-5
Disciplines
  • Biology

Abstract

Abstract A strain with an elevated level of spontaneous mutations and an especially high rate of reversion at a specific locus ( pab − ) was identified. The mutator trait is recessive. UV sensitivity and the absence of a UV-specific endonucleolytic activity were associated with the enhancement of the mutation rate in mutator strains. The endonuclease associated with the regulation of the mutation rate also acted on single-stranded DNA. The molecular weight of this enzyme is about 38 000 daltons.

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