Affordable Access

Publisher Website

Environ-friendly approaches to densely functionalized β-lactams

Authors
Journal
Tetrahedron Letters
0040-4039
Publisher
Elsevier
Publication Date
Volume
38
Issue
5
Identifiers
DOI: 10.1016/s0040-4039(96)02421-5
Disciplines
  • Chemistry

Abstract

Abstract A convenient approach to densely functionalized α-allyl-β-lactams has been developed using organometallic reagents and α-keto-β-lactams. Indium mediated Barbier reaction in aqueous media proceeded with a higher level of diastereoselectivity and chemical yield than zinc mediated Barbier reaction in anhydrous organic solvents.

There are no comments yet on this publication. Be the first to share your thoughts.