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Abscopal depression of G-CSF mobilized peripheral stem cells.

Authors
Type
Published Article
Journal
Bone Marrow Transplantation
0268-3369
Publisher
Nature Publishing Group
Publication Date
Volume
14
Issue
6
Pages
1005–1007
Identifiers
PMID: 7536066
Source
Medline

Abstract

Transient suppression of hematopoietic colony formation from cytokine mobilized PBSC was observed in a patient following local radiation therapy for lymphoma. This effect was seen 2 weeks after completion of radiation and reversed by 6 weeks. The patient successfully engrafted after myeloablative chemotherapy with harvested PBSC. This report documents the first reported case of suppression of PBSC colony formation following radiation and we speculate that this finding may be due to an abscopal effect.

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