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Abp1p and cortactin, new "hand-holds" for actin.

Authors
  • Olazabal, I M
  • Machesky, L M
Type
Published Article
Journal
The Journal of cell biology
Publication Date
Aug 20, 2001
Volume
154
Issue
4
Pages
679–682
Identifiers
PMID: 11514584
Source
Medline
License
Unknown

Abstract

Recently, two new ligands of the Arp2/3 complex have been described that may shed light on the way cells organize complex networks of actin in response to signals. Abp1p, a yeast protein involved in endocytosis, and cortactin, a mammalian src substrate, both enhance the ability of the Arp2/3 complex to assemble branched actin filament networks.

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