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Abnormalities in the normal appearing white matter of the cerebral hemisphere contralateral to a malignant brain tumor detected by diffusion tensor imaging.

Authors
  • Kallenberg, Kai
  • Goldmann, Torben
  • Menke, Jan
  • Strik, Herwig
  • Bock, Hans C
  • Mohr, Alexander
  • Buhk, Jan H
  • Frahm, Jens
  • Dechent, Peter
  • Knauth, Michael
Type
Published Article
Journal
Folia neuropathologica / Association of Polish Neuropathologists and Medical Research Centre, Polish Academy of Sciences
Publication Date
Jan 01, 2014
Volume
52
Issue
3
Pages
226–233
Identifiers
PMID: 25310733
Source
Medline
License
Unknown

Abstract

In patients with previously untreated anaplastic astrocytoma or glioblastoma, an increase of the ADC and a reduction of FA were found in the brain parenchyma of the hemisphere contralateral to the tumor localization. In the absence of visible MRI abnormalities, this may be an early indicator of microstructural changes of the NAWM attributed to malignant brain tumor.

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