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Abnormal fiber end migration in Royal College of Surgeons rats during posterior subcapsular cataract formation.

Authors
  • Joy, Anita
  • Mohammed, Tabraiz A
  • Al-Ghoul, Kristin J
Type
Published Article
Journal
Molecular vision
Publication Date
Jan 01, 2010
Volume
16
Pages
1453–1466
Identifiers
PMID: 20806082
Source
Medline
License
Unknown

Abstract

The data are consistent with the hypothesis that migration of basal fiber ends is altered in a two stage process wherein initially, migration patterns undergo a rapid shift resulting in abnormal suture sub-branch formation. Subsequent cytological alterations are consistent with an eventual cessation of migration, precluding proper targeting of basal ends to their sutural destinations and leading to cataract plaque formation.

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