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Osteoblast responses to tape-cast and sintered bioactive glass ceramics.

Authors
Journal
Journal of Biomedical Materials Research Part A
1549-3296
Publisher
Wiley Blackwell (John Wiley & Sons)
Publication Date
Keywords
  • Prosthetic Materials And Prosthetics (Bioactive Glass
  • Osteoblast Responses To Tape-Cast And Sintered Bioactive Glass Ceramics)
  • Adhesion
  • Apoptosis
  • Bone Formation
  • Human
  • Osteoblast (Osteoblast Responses To Tape-Cast And Sintered Bioactive Glass Ceramics)
Disciplines
  • Engineering

Abstract

The advantage of tape-cast bioactive glasses lies in the manufg. procedure, which allows the build-up of layers and, therefore, the prodn. of complex shapes. This, therefore, has applications to tissue engineering, where specific shapes are required such as repair of craniofacial defects. The bioactivity of tape-cast disks sintered at temps. ranging from 800 Deg to 1000 Deg and for 3 or 6 h was analyzed by FTIR. Tape-cast disks were used to culture primary human osteoblasts, and cell attachment, cell death, collagen prodn., nodule formation, and mineralization were studied. These responses were dependent upon Si and Na release profiles of the tape-cast disks, and development of the hydroxyapatite layer. [on SciFinder (R)]

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