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Selection for High Mutation Rates in Chemostats

Authors
Journal
Genetics
0016-6731
Publisher
The Genetics Society of America
Publication Date
Keywords
  • Investigations

Abstract

Competition experiments in chemostats show that mutator populations of Escherichia coli are more fit than wild type. The increased fitness can be explained by the appearance of new mutants better adapted to the chemostat environment. Fitness values vary between chemostats and are strongly correlated (P < 0.001) with fluctuations in population density.

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