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AA amyloidosis: Mount Sinai experience, 1997-2012.

Authors
  • Bunker, Daniel
  • Gorevic, Peter
Type
Published Article
Journal
Mount Sinai Journal of Medicine A Journal of Translational and Personalized Medicine
Publisher
Wiley (John Wiley & Sons)
Publication Date
Jan 01, 2012
Volume
79
Issue
6
Pages
749–756
Identifiers
DOI: 10.1002/msj.21342
PMID: 23239212
Source
Medline
License
Unknown

Abstract

Our study confirms the increasing number of patients being seen with idiopathic AA amyloidosis. More research is needed to determine if these patients have an underlying genetic susceptibility encoded in pyrin or other genes. Our study also confirms the dominance of renal disease in this population. The elevated levels of interleukin-6, in comparison with other cytokines, could represent a therapeutic target.

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