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[AA amyloidosis with cutaneous manifestations. Report of one case].

Authors
  • Fich S, Félix
  • Chahuán Y, Marco
  • Farías N, Ma Magdalena
  • Cárdenas D, Consuelo
  • Abarzúa A, Alvaro
  • Araya C, Gabriela
  • González B, Sergio
Type
Published Article
Journal
Revista médica de Chile
Publisher
SciELO Comision Nacional de Investigacion Cientifica Y Tecnologica
Publication Date
Apr 01, 2012
Volume
140
Issue
4
Pages
499–502
Identifiers
DOI: 10.4067/S0034-98872012000400011
PMID: 22854696
Source
Medline
License
Unknown

Abstract

Systemic amyloidosis is a rare disease that can affect any organ. Its clinical manifestations are varied and nonspecific. The skin involvement of this disease is common and can be easily recognized on physical examination. We report a 57-year-old male presenting with a two years history of malaise, dyspnea and myalgias. On physical examination, ungueal dystrophy, orange pigmentation of eyelids with periocular petechiae and mild macroglossia were observed. Incisional biopsies of the eyelids, cheeks and hands were obtained. The pathological study demonstrated amyloid deposits. Since protein electrophoresis was normal, the diagnosis of AA amyloidosis was postulated.

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