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The Fetus as a Cardiac Patient: Assessment and Therapy of Cardiovascular Pathology before Birth

International Journal of Pediatrics
Hindawi Publishing Corporation
Publication Date
DOI: 10.1155/2010/974520
  • Editorial
  • Biology
  • Medicine
  • Physics


Hindawi Publishing Corporation International Journal of Pediatrics Volume 2010, Article ID 974520, 2 pages doi:10.1155/2010/974520 Editorial The Fetus as a Cardiac Patient: Assessment and Therapy of Cardiovascular Pathology before Birth Anita J. Moon-Grady,1 Shinjiro Hirose,1 Greg Kesby,2 Samuel Menahem,3 and Wayne Tworetzky4 1 Fetal Treatment Center, University of California San Francisco, CA 94143, USA 2Department of High Risk Obstetrics and Fetal Medicine, Royal Prince Alfred Hospital, Sydney, NSW 2050, Australia 3 Fetal Cardiac Unit and Department of Pediatrics, Monash Medical Centre, Melbourne, VIC 3168, Australia 4Advanced Fetal Care Center, Children’s Hospital Boston, Boston, MA 02115, USA Correspondence should be addressed to Anita J. Moon-Grady, [email protected] Received 2 November 2010; Accepted 2 November 2010 Copyright © 2010 Anita J. Moon-Grady et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The past few decades have seen major advances in evaluation and treatment of fetal cardiovascular diseases. Largely due to advances in imaging, recognition of structural pathology in the developing human heart can now be performed as early as the 12th week of pregnancy and can be seen to develop and progress through gestation. Because of the observation that serious structural congenital heart disease may progress from seemingly minor disease if untreated, several centers are now intervening before birth to address such abnormalities and attempt to prevent the further development of structural disease. Furthermore, detailed assessment of cardiac rhythm, function, and myocardial mechanics is now also possible as early as the first trimester. Transplacental treatment for fetal rhythm abnormalities has dramatically changed the outcomes for affected pregnancies in the past decade. More recent

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