Emergency and critical care principles are similar for all mammals. However, because they are stressed easily, rabbits require specialized handling techniques. Rabbits must be evaluated efficiently and stabilized quickly before moving into the definitive diagnostic phase of their care. A thorough clinical history, systematic physical examination, and multiple diagnostic tests are ideal, but when a rabbit is in critical condition, emergency stabilization and fluid resuscitation must take priority. Common emergency presentations include gastrointestinal disorders, such as prolonged anorexia, respiratory distress, neoplasia, neurologic symptoms, exposure to toxins, trauma, and urinary tract infections or obstruction.