Affordable Access

A circular dichroism study of DNA-basic peptides associations in the absence or in the presence of Ca++.

Publication Date


The interaction of DNA with basic peptides (Lys methyl ester*, Lys2, (Lys)2methyl ester) has been studied by circular dichroism. The changes of the DNA CD spectra in the presence of peptides are interpreted as a transconformation from the B form to the C form of DNA. The presence of Ca++ in the mixture induces a supplementary transconformation. These observations suggest Ca++-basic peptides-DNA complexes as a structural model for chromatin.

There are no comments yet on this publication. Be the first to share your thoughts.