The transcondylar approach is a skull-base technique that enables neurosurgeons to access the anterior brain stem and foramen magnum region with minimum retraction. This extension of the unilateral suboccipital approach optimizes the surgical treatment of lesions in this region, including benign tumors, bony and locally invasive tumors, and vascular lesions. Many variations of the lateral skull-base approach to the anterior craniovertebral junction, which include variable resection of the condyle, have been published. This article summarizes some of these variations and describes the far-lateral transcondylar approach as performed at our institution. It also reviews the indications, advantages, and disadvantages of the approach.