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The Effect of Core Surface Tension on Roughness of Film – Coated Tablets

Iranian Journal of Pharmaceutical Research
Publication Date
  • Film Coating
  • Plasticizer Molecular Weight
  • Surface Free Energy
  • Arithmetic Mean Roughness.
  • Mathematics


The arithmetic mean roughness, Ra, values were determined by scanning electron microscopic technique of different core models (furazolidone, nitrofurantoin and acetyl salicylic acid), coated by HPMC film forming solution containing 10 wt% of various molecular weight PEGs. The results showed that both plasticizer molecular weight and core surface free energy could have a significant influence on Ra.

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