Regional competitiveness is the crucial area of research in modern economics. The European Union uses the regional competitiveness and divergences studies in creating the European Member States economies competitive advantages. Regional competitiveness determinates also the enterprises competitiveness advantages and plays the crucial role in creating their competitiveness position. The importance of the regional competiveness increases in the knowledge-based economy circumstances, where competitiveness depends on the ability to use knowledge, skills and attitudes of entrepreneurship. Regions are the leaders responsible for these resources mobilization so identification of their strengths and weaknesses allows to indicate the crucial growth tools. In terms of traditional concept, competitiveness is based on the classical theories of absolute advantage by Smith, Ricardo‘s comparative advantage to the first theory of Porter‘s competitive advantage. Modern knowledge-based economy creates a new approach to regional competitiveness researches – from the advanced Porter competitive advantage theory to the dynamic concept of constructed advantages. The key element of constructed advantages theory is an eclectic approach that combines a variety of different concepts such as Regional Innovation Systems, Triple Helix-concept and public-private partnership. They are characterized by multi-directional and multi-dimensional interactions between the actors of the economy. The purpose of the analysis is a preliminary assessment of selected economic relations between the entities in Pomeranian region. There be analyzed relations between business and research and development institutions with particular emphasis on the role of Science and Technology Park in Gdynia as an institution affecting the shape and strength of relationships that create advantages of the region.