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Interactions between antimicrobial drugs and phagocytes: an overview

Authors
Journal
International Journal of Antimicrobial Agents
0924-8579
Publisher
Elsevier
Publication Date
Volume
3
Issue
2
Identifiers
DOI: 10.1016/0924-8579(93)90017-y
Keywords
  • Phagocyte
  • Immunomodulation
  • Antimicrobial Agents
Disciplines
  • Medicine

Abstract

Abstract The problems of microbial resistance and the increasing numbers of immunocompromised individuals have strengthened interest in new therapeutic strategies, including immunomodulation. Since phagocytes play both positive and deleterious roles in infectious diseases, they may be criticl targets in the study of drug-induced immunomodulation. Antimicrobial agents can modify phagocyte numbers] and functions in many ways. The main data and the implications of such interferences are reviewed in this paper.

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