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Computed axial brain tomograms in long-term benzodiazepine users

Authors
Journal
Psychiatry Research
0165-1781
Publisher
Elsevier
Publication Date
Volume
48
Issue
2
Identifiers
DOI: 10.1016/0165-1781(93)90037-h
Keywords
  • Computed Tomography
  • Anxiety
  • Depression
  • Ventricle-To-Brain Ratio
  • Lorazepam
Disciplines
  • Medicine

Abstract

Abstract Computed axial brain tomograms were recorded in four groups of subjects: (a) subjects who had never taken benzodiazepines (n = 25); (b) subjects who had taken them in the past for less than a year (n = 9); (c) patients currently taking benzodiazepines (n = 30); and (d) patients who had taken benzodiazepines in the past for at least a year and who had been withdrawn from medication for at least 6 months (n = 17). Ventricle-to-brain ratios and tissue absorption to X-rays were computed. No overall differences were found between the main groups. However, a few brain regions differed in density between nonusers and heavy users, particularly those taking lorazepam.

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