In experiment an antitumoral efficiency of electrochemical lysis (ECL) was estimated on an example sarcoma M-1, some various combination of ECL parameters (current strength, time of influence) were investigated. By estimate of results we can see that with increase of parameters a percent of full tumor regression goes up. It was confirmed by investigation of the morphological section. In clinik by performance of ECL to patient with breast cancer the medicinal pathomorphism 3 stages was achieved. In observation period we haven't received the date about metastasis.