Affordable Access

Adhesion-mediated signaling in the regulation of mammary epithelial cell survival.

Authors
Journal
Journal of Mammary Gland Biology and Neoplasia
1083-3021
Publisher
Springer-Verlag
Publication Date

Abstract

Tissue architecture in multicellular organisms is maintained through adhesive interactions between cells and their neighbors, and between cells and the underlying extracellular matrix. These interactions are important in the dynamic regulation of tissue organization as well as the control of cell proliferation, differentiation and apoptosis. The ultimate goal of this regulation is to promote cell growth and differentiation only when the cell is in the correct location, and to delete cells that have become displaced from their proper environment. It therefore plays an important role in development and tissue remodeling. In this review we consider the molecular mechanisms by which cell-matrix interactions contribute to cell survival, and discuss their role in mammary gland development and function.

There are no comments yet on this publication. Be the first to share your thoughts.

Statistics

Seen <100 times
0 Comments

More articles like this

Adhesion-mediated signaling in the regulation of m...

on Journal of Mammary Gland Biolo... April 1999

The RhoA-Rok-Myosin II Pathway is Involved in Extr...

on Journal of Cellular Physiology Jun 15, 2011

The RhoA-Rok-myosin II pathway is involved in extr...

on Journal of Cellular Physiology Jun 15, 2011

Involvement of Rho signaling in PAR2-mediated regu...

on European Journal of Pharmacolo... Jan 01, 2006
More articles like this..