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Understanding the insertion of transporters and other membrane proteins

Authors
Journal
Current Opinion in Cell Biology
0955-0674
Publisher
Elsevier
Publication Date
Volume
12
Issue
4
Identifiers
DOI: 10.1016/s0955-0674(00)00113-7
Keywords
  • Membrane

Abstract

Abstract Recent studies show that transporters integrate into the lipid bilayer using topogenic sequences present throughout the entire polypeptide chain. These topogenic sequences can act in unpredictable ways with new translocation/stop transfer activities. In addition, a new membrane-insertion pathway has been identified in bacteria with homologs in mitochondria and chloroplasts.

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